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Masaaki Murai Selected Research

1- (2- (1- adamantyl)ethyl)- 1- pentyl- 3- (3- (4- pyridyl)propyl)urea

2/2010Transient receptor potential vanilloid 1 agonists as candidates for anti-inflammatory and immunomodulatory agents.
1/2010Effects of SA13353, a transient receptor potential vanilloid 1 agonist, on leukocyte infiltration in lipopolysaccharide-induced acute lung injury and ovalbumin-induced allergic airway inflammation.
4/2009Preventive effect of SA13353 [1-[2-(1-adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea], a novel transient receptor potential vanilloid 1 agonist, on ischemia/reperfusion-induced renal injury in rats.
7/2008SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons mediated via transient receptor potential vanilloid 1 in vivo.

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Masaaki Murai Research Topics

Disease

2Inflammation (Inflammations)
02/2010 - 01/2010
2Experimental Arthritis
04/2009 - 07/2008
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
02/2010
1Acute Lung Injury
01/2010
1Encephalomyelitis (Myeloencephalitis)
01/2010
1Lung Injury
01/2010
1Arthritis (Polyarthritis)
01/2010
1Acute Kidney Injury (Acute Renal Failure)
04/2009
1Ischemia
04/2009
1Rheumatoid Arthritis
07/2008

Drug/Important Bio-Agent (IBA)

41- (2- (1- adamantyl)ethyl)- 1- pentyl- 3- (3- (4- pyridyl)propyl)ureaIBA
02/2010 - 07/2008
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2010 - 07/2008
2CytokinesIBA
02/2010 - 04/2009
2LipopolysaccharidesIBA
02/2010 - 01/2010
1Interleukin-4 (Interleukin 4)IBA
01/2010
1Interleukin-12 Subunit p40IBA
01/2010
1OvalbuminIBA
01/2010
1Capsaicin (Zostrix)FDA Link
04/2009
1Messenger RNA (mRNA)IBA
04/2009
1Superoxides (Superoxide)IBA
04/2009
1Urea (Carbamide)FDA LinkGeneric
04/2009
1Interleukin-10 (Interleukin 10)IBA
04/2009
1resiniferatoxinIBA
04/2009

Therapy/Procedure

1Nephrectomy
04/2009